What is proBNP normal range?
A normal level of NT-proBNP, based on Cleveland Clinic’s Reference Range is: Less than 125 pg/mL for patients aged 0-74 years. Less than 450 pg/mL for patients aged 75-99 years.
What is proBNP level?
If your BNP or NT-proBNP levels were higher than normal, it probably means you have heart failure. Usually, the higher the level, the more serious your condition is. If your BNP or NT-proBNP results were normal, it probably means your symptoms are not being caused by heart failure.
What is a good BNP result?
Experts agree there is a healthy range for BNP levels. The cut-off point can vary by laboratory, but commonly, this range is less than 100 picograms of BNP per milliliter (pg/ml) of blood. This means that a result of more than 100 pg/ml indicates the possibility of heart failure.
What NT-proBNP indicates heart failure?
While a cut point of 300 pg/ml is proposed to rule out the diagnosis of heart failure, for patients younger than 50 years old, between 50-75 and above 75 NT-proBNP levels respectively > 450 pg/ml, > 900 pg/ml, and > 1800 pg/ml have high likelihood of heart failure.
How do you interpret BNP?
Interpreting BNP Measurements for Heart Failure in Different Clinical Settings. BNP = brain natriuretic peptide; LR+ = positive likelihood ratio; LR– = negative likelihood ratio. *—Based on an assumed LR+ of 5.0 for > 150 pg per mL, LR+ of 0.57 for 50 to 150 pg per mL, and LR– of 0.08 for < 50 pg per mL.
How high can pro-BNP go?
1. Myocardial Stress/Injury
| Cut-off Value | ||
|---|---|---|
| Acute Dyspnea | To exclude acute HF | |
| BNP | <30-50 pg/mL | |
| NT-proBNP | <300 pg/mL | |
| To identify acute HF |
What is difference between BNP and proBNP?
KEY TAKEAWAYS. Differences between BNP and NT-proBNP on a biological level really relate to the fact that one is biologically active as a hormone, BNP, whereas NT-proBNP is cleared passively from the body and is not biologically active. Therefore, BNP has a much shorter half-life, NT-proBNP has a longer half-life.
What does a BNP level of 1600 mean?
BNP levels go up when the heart cannot pump the way it should. A result greater than 100 pg/mL is abnormal. The higher the number, the more likely heart failure is present and the more severe it is. Sometimes other conditions can cause high BNP levels.
What does a BNP of 20000 mean?
[6], who also found high BNP levels (4000–20,000 pg/mL) were associated with kidney dysfunction. Although the data are inconsistent, our results suggest in elderly patients, the extreme NT pro-BNP may be more useful for the assessment of the severity of impaired renal function.