What is a leiomyomas?
(LY-oh-my-OH-muh) A benign smooth muscle tumor, usually in the uterus or gastrointestinal tract. Also called fibroid.
What is the most common type of leiomyoma?
Intramural leiomyomas arise within the wall of the uterus. They are the most common type of leiomyomas, and can be associated with infertility, miscarriage, fetal malpresentation, and preterm birth.
Where do leiomyomas occur?
Leiomyoma describes a benign growth of smooth muscle tissue. These tumors can occur anywhere in the body where smooth muscle is found such as the skin, the eyes, the uterus (commonly called fibroids), the bladder, and the gastrointestinal and respiratory tracts.
How are leiomyomas classified?
Leiomyomas are classified into subgroups based on their location within the layers of the uterus. Myomas are classified as intramural (within the myometrium), subserosal (found just below the uterine serosa), or submucosal (located just beneath the endometrium) (Fig. 19‐1).
What is a common complication of leiomyomas?
COMPLICATIONS. Clinical problems associated with leiomyomas are related to pregnancy, infertility, abnormal bleeding, large masses, pain, and sarcomatous changes.
What is another name for leiomyoma?
Leiomyomas, also known as fibroids, are a group of benign smooth muscle tumors commonly present in premenopausal women. These tumors are of monoclonal origin which arises from the smooth muscle of the uterus.
Is a leiomyoma a tumor?
Leiomyomas are benign tumors arising from smooth muscle, most commonly seen in uterine myometrium, gastrointestinal tract, skin and lower extremities of middle-aged women.
What are the different types of leiomyomas?
In be- tween, there are several leiomyoma variants, such as mitotically active, cellular, and atyp – ical leiomyomas, as well as smooth muscle tumors of uncertain malignant potential (STUMP). Uterine leiomyomas are the most
What is the pathophysiology of leiomyomata?
Uterine leiomyomata are a common cause of reproductive health problems and medical care utilization in women. Estrogen and progesterone are almost certainly involved in their pathogenesis, but the mechanisms through which these hormones act are not well defined at the molecular or epidemiologic levels.
Is adjuvant therapy indicated for leiomyoma variants?
However, overwhelming- ly, the leiomyoma variants behave in a clini- cally benign fashion and require no adjuvant therapy [8]. The two leiomyoma variants that Review of Leiomyoma Variants Elizabeth Kagan Arleo1 Peter E. Schwartz2 Pei Hui3 Shirley McCarthy4 Arleo EK, Schwartz PE, Hui P, McCarthy S 1Weill Cornell Imaging, New York-Presbyterian/
What is the pathophysiology of uterine leiomyomas?
The pathophysiology of uterine leiomyomas is uncertain. Therefore, therapeutic approaches have been primarily empirical. It is now well documented that growth factors control the functional and possibly the histological integrity of several tissues.