How accurate is CA-125 in detecting ovarian cancer?

Results: Using a CA125 cutoff of 30 U/mL, an overall sensitivity of 94.8% (96.6% specificity) was obtained when comparing malignancies versus healthy postmenopausal controls, whereas a cutoff of 65 U/mL provided a sensitivity of 83.9% (99.6% specificity).

What is a normal CA-125 result?

CA-125 normal range The range of 0 to 35 U/mL is considered within the normal guidelines. Levels over 35 U/mL may indicate the presence of cancer or other conditions. Not all patients with a high CA-125 result have cancer. For women with no ovarian cancer history, a high result usually leads to additional testing.

How quickly does CA-125 rise?

The average time from serum CA125 increase to detection of a recurrent lesion by physical or imaging examination was about 3 months. It is not recommend chemotherapy when patients serum CA125 increased alone after post-treatment.

What are the benign causes of elevated ca 125 levels?

Lets us now discuss the benign or non-dangerous conditions that may elevate the CEA 125 level. Benign Causes of Elevated CEA 125 level. Benign or non-cancerous causes are those which are relatively non-dangerous or are not life-threatening. These include: Ovarian cyst.

What is a normal CA125 level?

The normal range for CA 125 is 0 to 35 units/ml.While a CA 125 level over 35 may indicate cancer, it does not always mean the person has cancer. A CA 125 level over 35 is only a potential indicator.. If a woman has not been previously diagnosed with ovarian cancer, high levels indicate further testing is needed to make a diagnosis.

What should CA125 levels be?

The normal value is less than 46 U/mL. If your CA 125 level is higher than normal, you may have a benign condition, or the test result could mean that you have ovarian, endometrial, peritoneal or fallopian tube cancer. Your doctor may recommend other tests and procedures to determine your diagnosis.

What should your ca 125 level be?

The normal range for CA 125 is 0 to 35 units/ml. While a CA 125 level over 35 may indicate cancer, it does not always mean the person has cancer. A CA 125 level over 35 is only a potential indicator. If a woman has not been previously diagnosed with ovarian cancer, high levels indicate further testing is needed to make a diagnosis.